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CHGA Human, His/重组人嗜铬粒蛋白A, His

点击次数:169发布时间:2012/11/2 15:23:16

CHGA Human, His/重组人嗜铬粒蛋白A, His

更新日期:2024/10/16 16:00:43

所 在 地:美洲

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简单介绍:CHGA Human, His/重组人嗜铬粒蛋白A, His

相关标签:CHGA Human  His 重组人嗜铬粒蛋白A  His 

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CHGA Human, His/重组人嗜铬粒蛋白A, His

产品编号:PRO-699
产品规格:5μg/20μg/1mg
 
 
 
 
Synonyms CGA, CHGA, Vasostatin-2, Pituitary secretory protein I, SP-I.
Introduction chromgranin-A is part of the neuroendocrine secretory protein family. CHGA is located in secretory vesicles of neurons and endocrine cells. chromgranin-A is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. chromgranin-A has numerous biological activities on some tissues and organs and exerts a large spectrum of homeostatic actions, including antifungal and antimicrobial effect, modulation of cell adhesion, and inhibition of parathyroid hormone secretion.
Description Recombinant Human CHGA produced in E.Coli is a single, non-glycosylated polypeptide chain containing 477 amino acids (19-457 a.a) and having a molecular mass of 53.3 kDa.
chromgranin-A is fused to 37 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile filtered colorless solution.
Formulation The CHGA protein contains 20mM MES buffer pH-6, 2mM EDTA, 0.1mM PMSF and 10% glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity Greater than 85.0% as determined by Analysis by SDS-PAGE.
Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMLP VNSPMNKGDT EVMKCIVEVI SDTLSKPSPM PVSQECFETL RGDERILSIL RHQNLLKELQ DLALQGAKER AHQQKKHSGF EDELSEVLEN QSSQAELKEA VEEPSSKDVM EKREDSKEAE KSGEATDGAR PQALPEPMQESKAEGNNQAP GEEEEEEEEA TNTHPPASLP SQKYPGPQAE GDSEGLSQGL VDREKGLSAE PGWQAKREEE EEEEEEAEAG EEAVPEEEGPTVVLNPHPSL GYKEIRKGES RSEALAVDGA GKPGAEEAQD PEGKGEQEHS QQKEEEEEMA VVPQGLFRGG KSGELEQEEE RLSKEWEDSKRWSKMDQLAK ELTAEKRLEG QEEEEDNRDS SMKLSFRARA YGFRGPGPQL RRGWRPSSRE DSLEAGLPLQ VRGYPEEKKE EEGSANRRPEDQELESLSAI EAELEKVAHQ LQALRRG.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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