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BAG1 Human/重组人BCL2联系永生基因1

点击次数:202发布时间:2012/11/2 19:11:57

BAG1 Human/重组人BCL2联系永生基因1

更新日期:2024/10/16 16:00:43

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简单介绍:BAG1 Human/重组人BCL2联系永生基因1

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BAG1 Human/重组人BCL2联系永生基因1

产品编号:PRO-817
产品规格:5μg/20μg/1mg
 
 
 
Synonyms BAG-1, Bcl-2-associated athanogene 1, RAP46, Bcl-2-binding protein, HAP.
Introduction BAG1 binds to BCL2 and is also called BCL2-associated athanogene. BAG1 increases the anti-apoptotic effects of BCL2 and is characterizes as a link between growth factor receptors and anti-apoptotic mechanisms. BAG1 inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. BAG1 inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. BAG1 enhances the anti-cell death function of BCL2 induced by various stimuli.
Description BAG1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 230 amino acids (1-230 a.a.) and having a molecular mass of 25.9 kDa. BAG1 protein is purified by standard chromatography.
Source Escherichia Coli.
Physical Appearance Sterile filtered colorless solution.
Formulation BAG1 Human solution containing 20mM Trsi HCL pH-8, 0.1M NaCl and 10% glycerol.
Stability BAG1 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino acid sequence MNRSQEVTRD EESTRSEEVT REEMAAAGLT VTVTHSNEKH DLHVTSQQGS SEPVVQDLAQ VVEEVIGVPQ SFQKLIFKGK SLKEMETPLS ALGIQDGCRV MLIGKKNSPQ EEVELKKLKH LEKSVEKIAD QLEELNKELT GIQQGFLPKD LQAEALCKLD RRVKATIEQF MKILEEIDTL ILPENFKDSR LKRKGLVKKV QAFLAECDTV EQNICQETER LQSTNFALAE.
Purity Greater than 90% as determined by SDS-PAGE.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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