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HCV NS4 (1916-1947 a.a.)/重组丙型肝炎病毒NS4(1916-1947 a.a.)

点击次数:210发布时间:2012/11/9 18:40:54

HCV NS4 (1916-1947 a.a.)/重组丙型肝炎病毒NS4(1916-1947 a.a.)

更新日期:2024/10/16 16:00:55

所 在 地:美洲

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简单介绍:HCV NS4 (1916-1947 a.a.)/重组丙型肝炎病毒NS4(1916-1947 a.a.)

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HCV NS4 (1916-1947 a.a.)/重组丙型肝炎病毒NS4(1916-1947 a.a.)

产品编号:HCV-202
产品规格:100μg/500μg/1mg
 
 
 
Introduction HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae.
HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Description E.coli derived 30 kDa recombinant protein.
Artificial mosaic polypeptide composite constructed from diagnostically relevant antigenic regions derived from the NS4 region.
Purification Method HCV NS4 protein was purified by proprietary chromatographic technique.
Purity HCV NS4 protein is >95% pure as determined by 10% PAGE (coomassie staining).
Formulation 1.5M urea, 25mM Tris-HCl pH-8, 0.2% Triton-X & 50% Glycerol.
Storage HCV NS4 protein is shipped at ambient temperature.
Upon arrival, Store at -20°C.
Stability Five years frozen. One month in solution at room temperature.
Specificity Immunoreactive with sera of HCV-infected individuals.
Applications HCV NS4 antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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