产品展示
CYP2D6/ 重组人细胞色素P450 2D6
点击次数：352发布时间：2012/11/17 15:08:51
更新日期：2024/10/16 16:00:55
所 在 地：欧洲
产品型号：
优质供应
详细内容
慧嘉生物您实验身边的好伙伴
为客户提供“品质的产品”和“*优质的服务”
AssayBiotech CUSABIO Immunoway Santa Abcam Cst jackson Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec lifespan BD
欢迎广大客户咨询，另有大量宣传海报和小礼品赠送。
网站：www.biohj.com
Q Q：
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
Synonyms Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. Introduction Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male.
The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. Description Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.
The LKM1 is purified by proprietary chromatographic techniques. Source Sf9 insect cells. Physical Appearance Sterile filtered liquid formulation. Formulation LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. Applications Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. Coating concentration 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Purity Greater than 40% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
CYP2D6/ 重组人细胞色素P450 2D6
产品编号：ENZ-316
产品规格：5μg/20μg/1mg
产品规格：5μg/20μg/1mg
| Synonyms | Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1. |
| Introduction | Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes （mono-oxygenases） present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1） which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV ａnd 2b without HCV. AIH 2a patients are often over 40 ａnd predominantly male. The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques. |
| Description | Cytochrome P450 2D6 Human Recombinant （also called liver/kidney microsomal antigen 1） produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton. The LKM1 is purified by proprietary chromatographic techniques. |
| Source | Sf9 insect cells. |
| Physical Appearance | Sterile filtered liquid formulation. |
| Formulation | LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT ａnd 1% Triton X-100. |
| Immunological functions | 1. Binds IgG-type human auto-antibodies. 2. Standard ELISA test （checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387）. |
| Applications | Western-Blot with monoclonal anti-LKM-1 antibody ａnd autoimmune hepatitis patient sera. |
| Coating concentration | 0.35-0.6 μg/ml （depending on the type of ELISA plate ａnd coating buffer）. Suitable for biotinylation ａnd iodination. |
| Storage Conditions | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°Cfor longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 40% as determined by SDS-PAGE. |
| Usage | Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
