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Rabbit Anti-Integrin alpha 2/CD49b
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Rabbit Anti-Integrin alpha 2/CD49b
FROM: SANTACRUZ
Catalog Number : RS-2635R
Quantity size : 0.2ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Background: Integrins are heterodimeric cell surface receptors composed of alpha ａnd beta subunits, which mediate cell-cell ａnd cell-extracellular matrix attachments. They are responsible for adhesion of platelets ａnd other cells to collagens, modulation of collagen ａnd collagenase gene expression, force generation ａnd organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth ａnd early metastatic capacity of melanoma cells.
Rabbit Anti-Integrin alpha 2/CD49b
Specificity : · anti- CD49b is a rabbit monoclonal antibody unconjugated
· specific for CD49b of hu, rat, mo
· epitope mapping in the C-terminalse of CD49b of hu, rat, mo
· use for western blotting, elisa, immunoprecipitation ａnd immunohistochemistry
· Protein G affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt: 34kDa
Application: ·Western blotting 1:100-500
·Immunohistochemistry 1:100-500
·ELISA 1:500-1000
·Optimal working dilutions must be determined by the end user.
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rabbit Anti-Integrin alpha 2/CD49b
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