本公司经销CD44/HCAM/PGP1，CD44抗体，克隆类型为polyclonal，宿主来源是Rabbit，CD44/HCAM/PGP1CD44抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0521R
英文名称：Anti-CD44/HCAM/PGP1
中文名称：CD44抗体
其他名称：CD 44; CD44 isoform RC; CD44 molecule; CDw44; Cell surface glycoprotein CD44; ECM III; ECMR III; ECMRIII; Epican; Extracellular Matrix Receptor III; GP90 Lymphocyte Homing Adhesion Receptor; HCAM; HCELL; Heparan Sulfate Proteoglycan; Hermes Antigen; HUTCH I; HUTCH1; Hyaluronate Receptor; IN; Indian blood group; Inlu Related p80 Glycoprotein; lhr; Ly 24; MC56; MDU2; MDU3; MGC10468; MIC4; MUTCH I; MUTCH1; PGP 1; PGP1; Phagocytic Glycoprotein 1; Phagocytic glycoprotein I.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 85kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, cow, hrs, Rb
产品介绍：The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion ａnd migration. It is a receptor for hyaluronic acid （HA） ａnd can also interact with other ligands, such as osteopontin, collagens, ａnd matrix metalloproteinases （MMPs）. This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation ａnd homing, hematopoiesis, ａnd tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural ａnd functional diversity of this protein, ａnd may be related to tumor metastasis. [provided by RefSeq].Subunit : Interacts with PKN2.Subcellular Location : Membrane; Single-pass type I membrane protein.Tissue Specificity : Isoform 10 （epithelial isoform） is expressed by cells of epithelium ａnd highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.Similarity : Contains 1 Link domain. CD44是一个重要的细胞表面粘附分子。它在许多类型的人类细胞上都表达，在很多生理和病理过程中有复杂的作用，例如细胞迁移和在肿瘤细胞的生长调控中。CD44传递着诸多的细胞通路，有研究者认为CD44是一个新的信号通路蛋白。CD44介导淋巴细胞与血管内皮细胞包括粘膜组织中高内皮小静脉的粘连，这可能是通过激活其它粘附分子而间接造成的。CD44也是肿瘤细胞浸润的重要因素。