本公司经销Cullin 5/CUL5，血管加压素激活钙启动受体蛋白1抗体，克隆类型为polyclonal，宿主来源是Rabbit，Cullin 5/CUL5血管加压素激活钙启动受体蛋白1抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-6784R
英文名称：Anti-Cullin 5/CUL5
中文名称：血管加压素激活钙启动受体蛋白1抗体
其他名称：CUL 5; CUL-5; CUL5; CUL5_HUMAN; Cullin-5; Cullin5; VACM 1; VACM-1; VACM1; Vasopressin activated calcium mobilizing receptor 1; Vasopressin activated calcium mobilizing receptor; Vasopressin-activated calcium-mobilizing receptor 1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 90kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, chk, dog, hrs, cow, Rb
产品介绍：Core component of multiple SCF-like ECS （Elongin-Cullin 2/5-SOCS-box protein） E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination ａnd subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate ａnd the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS（SOCS1） seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.Function : Core component of multiple SCF-like ECS （Elongin-Cullin 2/5-SOCS-box protein） E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination ａnd subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate ａnd the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS（SOCS1） seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.Subunit : Component of multiple ECS （Elongin BC-CUL2/5-SOCS-box protein） E3 ubiquitin-protein ligase complexes formed of CUL5, Elongin BC （TCEB1 ａnd TCEB2）, RBX2 ａnd a variable SOCS box domain-containing protein as substrate-specific recognition component. Component of the probable ECS（LRRC41） complex with the substrate recognition component LRRC41. Component of the probable ECS（SOCS1） complex with the substrate recognition component SOCS1. Component of the probable ECS（WSB1） complex with the substrate recognition subunit WSB1. Component of the probable ECS（SOCS3） complex with the substrate recognition component SOCS3. Component of the probable ECS（SPSB1） complex with the substrate recognition component SPSB1. Component of the probable ECS（SPSB2） complex with the substrate recognition component SPSB2. Component of the probable ECS（SPSB4） complex with the substrate recognition component SPSB4. Component of the probable ECS（RAB40C） complex with the substrate recognition subunit RAB40C. May also form complexes containing CUL5, elongin BC complex （TCEB1 ａnd TCEB2）, RBX1 ａnd TCEB3. May also form complexes containing CUL5, Elongin BC （TCEB1 ａnd TCEB2）, RBX1 ａnd VHL. The substrate recognition component can also be a viral protein such as HIV Vif, or human adenovirus 5 E1B large T-antigen ａnd E4-orf6. Interacts with RNF7/RBX2, LRRC41, SOCS3, SPSB1, SPSB2, SPSB4 ａnd RAB40C. Interacts with ASB1, ASB2, ASB6, ASB7 ａnd ASB12.Post-translational modifications : Neddylated. Deneddylated via its interaction with the COP9 signalosome （CSN） complex.Similarity : Belongs to the cullin family.