产品展示
CD83/HB15CD83抗体
点击次数：289发布时间：2012/12/3 20:57:42
更新日期：2024/9/5 14:42:48
所 在 地：中国大陆
产品型号：BY-2519R
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详细内容
货号：BY-2519R
英文名称：Anti-CD83/HB15
中文名称：CD83抗体
其他名称：B cell activation 45kDa cell surface glycoprotein Ig superfamily; B cell activation protein; BL11; BL11 PEN; CD83 molecule; Cell surface protein HB15; HB15; MGC130312; MGC130313; Cell surface protein HB15.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 23kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：The CD83 antigen is a 186 amino acid single chain glycoprotein. This molecule is a member of the immunoglobulin superfamily ａnd is composed of an extracellular V type immunoglobulin-like single domain, a transmembrane region, ａnd a short, 40 amino acid cytoplasmic tail. CD83 antigen undergoes extensive post translational glycosylation, as the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immunophenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also coexpress T cell markers （CD2, CD5）, B cell markers （CD40, CD78）, myeloid cell markers （CD13, CD33, CD36） ａnd cytokine receptors, as well as other cell surface molecules.Subunit : Monomer.Subcellular Location : Membrane; Single-pass type I membrane protein.Tissue Specificity : Abundantly expressed in spleen ａnd brain, but is also detected in most tissues analyzed.Similarity : Contains 1 Ig-like V-type （immunoglobulin-like） domain.
