产品展示
CHRNA2(neuronal)烟碱型乙酰胆碱受体A2(神经型)抗体
点击次数:260发布时间:2012/12/3 21:03:02
更新日期:2024/9/5 14:42:48
所 在 地:中国大陆
产品型号:BY-2538R
优质供应
详细内容
货号:BY-2538R
英文名称:Anti-CHRNA2(neuronal)
中文名称:烟碱型乙酰胆碱受体A2(神经型)抗体
其他名称: Nicotinic-Acetylcholine receptor; Chrna2; ACHR; CHRNA2; neuronal acetylcholine receptor subunit alpha-2 precursor; Acra-2; Acra2; BC011490; MGC18795.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 58kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, dog, Rb
产品介绍:Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq].