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CYP1A1细胞色素P450 1A1抗体
点击次数:175发布时间:2012/12/3 21:13:19
更新日期:2024/9/5 14:42:48
所 在 地:中国大陆
产品型号:BY-1606R
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货号:BY-1606R
英文名称:Anti-CYP1A1
中文名称:细胞色素P450 1A1抗体
其他名称:Cytochrome p450 1A1; AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX; AHH; AHRR; Aryl hydrocarbon hydroxylase; CYP 1; CYP1A1; CYPIA1; Cytochrome P1-450; Flavoprotein-linked monooxygenase; Microsomal monooxygenase; P1 450; P450 C; P450 form 6; P450 P1; Xenobiotic monooxygenase.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 58kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, pig
产品介绍:The Cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several cofactors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.Subcellular Location : Cytochrome P450 1A1: Cytoplasm.Cytochrome P450MT2A: Endoplasmic reticulum membrane. Mitochondrion membrane. Microsome membrane. Cytochrome P450MT2B: Endoplasmic reticulum. Mitochondrion.Tissue Specificity : Liver,Lung, lymphocytes and placenta.Similarity : Belongs to the cytochrome P450 family.合成与降解(Synthesis and Degradation)