产品展示
CYP21胆固醇21-羟化酶抗体
点击次数：249发布时间：2012/12/3 21:21:55
更新日期：2024/9/5 14:42:48
所 在 地：中国大陆
产品型号：BY-2443R
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详细内容
货号：BY-2443R
英文名称：Anti-CYP21
中文名称：胆固醇21-羟化酶抗体
其他名称：Cytochrome P450 21; cytochrome P450, family 21, subfamily A, polypeptide 2; 21-OH; 21OHA; 21OHB; CA21H; CAH1; CHOLESTEROL 21-HYDROXYLASE; CPS1; CYP21; Cyp21-ps1; Cyp21a1; CYP21A2; Cyp21a2-ps; CYP21B; CYP21OH-A; MGC150536; MGC150537; MGC156449; Oh21-1; Oh21-2; P450C21; P450c21B; CYP21A2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 54kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, pig, hrs, cow
产品介绍：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism ａnd synthesis of cholesterol, steroids ａnd other lipids. This protein localizes to the endoplasmic reticulum ａnd hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol ａnd aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene ａnd the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].Subcellular Location : Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.Similarity : Belongs to the cytochrome P450 family.
