产品展示
Calreticulin钙网蛋白抗体
点击次数:308发布时间:2012/12/3 21:22:12
更新日期:2024/9/5 14:42:48
所 在 地:中国大陆
产品型号:BY-5913R
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详细内容
货号:BY-5913R
英文名称:Anti-Calreticulin
中文名称:钙网蛋白抗体
其他名称:Autoantigen RO; CALR; CALR protein; CALR_HUMAN; Calregulin; Calreticulin; cC1qR; CRP55; CRTC; Endoplasmic reticulum resident protein 60; ERp60; grp60; HACBP; RO; Sicca syndrome antigen A; SSA.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 44kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, chk, pig, cow, dog, Rb
产品介绍:Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export.Subunit : Monomer. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Interacts with PDIA3/ERp57 (By similarity). Interacts with NR3C1 and TRIM21. Interacts with GABARAP.Subcellular Location : Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface.Similarity : Belongs to the calreticulin family.