本公司经销COLEC12，凝集胎盘蛋白1抗体，克隆类型为polyclonal，宿主来源是Rabbit，COLEC12凝集胎盘蛋白1抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-2541R
英文名称：Anti-COLEC12
中文名称：凝集胎盘蛋白1抗体
其他名称：Collectin placenta protein 1; Collectin placenta 1; Collectin-12; hCL-P1; CL-P1; Nurse cell scavenger receptor; Scavenger receptor with C-type lectin; Scavenger receptor class A member 4; COLEC12; CLP1; NSR2; SCARA4; SRCL. COL12_HUMAN
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 81kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, pig, cow, Rb
产品介绍：Colec12 is a member of the C-lectin family, proteins that possess collagen-like sequences ａnd carbohydrate recognition domains. Colec12 is a scavenger receptor that displays several functions associated with host defense. It promotes binding ａnd phagocytosis of Gram-positive, Gram-negative bacteria ａnd yeast ａnd mediates the recognition, internalization ａnd degradation of oxidatively modified low density lipoprotein （oxLDL） by vascular endothelial cells.Function : Scavenger receptor that displays several functions associated with host defense. Promotes binding ａnd phagocytosis of Gram-positive, Gram-negative bacteria ａnd yeast. Mediates the recognition, internalization ａnd degradation of oxidatively modified low density lipoprotein （oxLDL） by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- ａnd D-fucose, GalNAc, T ａnd Tn antigens in a calcium-dependent manner ａnd internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide ａnd asialo-orosomucoid （ASOR）. May also play a role in the clearance of amyloid beta in Alzheimer disease. Subunit : The extracellular domain forms a stable trimer. The extracellular domain interacts with fibrillar beta amyloid peptide. Subcellular Location : Membrane; Single-pass type II membrane protein. Note=Forms clusters on the cell surface. Tissue Specificity : Expressed in perivascular macrophages. Expressed in plaques-surrounding reactive astrocytes ａnd in perivascular astrocytes associated with cerebral amyloid angiopathy （CAA） in the temporal cortex of Alzheimer patient （at protein level）. Strongly expressed in placenta. Moderately expressed in heart, skeletal muscle, small intestine ａnd lung. Weakly expressed in brain, colon, thymus ａnd kidney. Expressed in nurse-like cells. Expressed in reactive astrocytes ａnd vascular/perivascular cells in the brain of Alzheimer patient. Similarity : Contains 1 C-type lectin domain. Contains 3 collagen-like domains. Database links : UniProtKB/Swiss-Prot: Q5KU26.3