产品展示
Cullin 2Cullin2抗体
点击次数：352发布时间：2012/12/3 21:31:37
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-4209R
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详细内容
货号：BY-4209R
英文名称：Anti-Cullin 2
中文名称：Cullin2抗体
其他名称：Cullin2; Cullin-2; CUL 2; MGC131970.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 87kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Cullin 2 is a member of the family of human Cullin genes （CUL1, 2, 3, 4a, 4b ａnd 5） homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor （HIF）. SIII is formed by three subunits: Elongin C, Elongin B ａnd VHL. Cullin 2 may serve as a rigid scaffold in the complex ａnd may contribute to catalysis through positioning of the substrate ａnd the ubiquitin-conjugating enzyme.
