产品展示
COUP-TF1转录因子COUP1抗体
点击次数：259发布时间：2012/12/3 21:35:01
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-11454R
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详细内容
货号：BY-11454R
英文名称：Anti-COUP-TF1
中文名称：转录因子COUP1抗体
其他名称：Chicken ovalbumin upstream promoter 1;chicken ovalbumin upstream promoter;COT1_HUMAN;COUP transcription factor 1;COUP transcription factor I;COUP-TF I;COUP TF1;EAR-3;EAR3;ERBAL3;NR2F1;NR2F2;Nuclear receptor subfamily 2 group F member 1;SVP44;TCFCOUP1;TFCOUP1;Transcription factor COUP 1;V ERBA related protein EAR 3;V-erbA-related protein 3.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 46kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow
产品介绍：COUP transcription factors have been cloned in several species ａnd identified as orphan members of the steroid/thyroid hormone receptor superfamily. COUP-TFI （also designated COUP or EAR-3） ａnd ARP-1 （also designated COUP-TFII） exhibit highly regulated ａnd overlapping expression in most tissues. COUP-TFs are highly expressed in the developing ａnd central nervous system, suggesting that these factors may be important in neural development ａnd differentiation. COUP-TFs can compete for binding to response elements which are common to other members of this family, including RAR, RXR, PPAR, HNF-4, VDR ａnd TR. They have been shown to act as negative regulators as well as initiators of transcription.Function : Coup （chicken ovalbumin upstream promoter） transcription factor binds to the ovalbumin promoter and, in conjunction with another protein （S300-II） stimulates initiation of transcription. Binds to both direct repeats ａnd palindromes of the 5＇-AGGTCA-3＇ motif. Represses transcriptional activity of LHCG.Subcellular Location : Nucleus.Similarity : Belongs to the nuclear hormone receptor family. NR2 subfamily.Contains 1 nuclear receptor DNA-binding domain.
