产品展示
CELSR3/Flamingo homolog 1表皮生长因子样蛋白1抗体
点击次数：218发布时间：2012/12/3 21:35:45
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-11460R
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详细内容
货号：BY-11460R
英文名称：Anti-CELSR3/Flamingo homolog 1
中文名称：表皮生长因子样蛋白1抗体
其他名称：Cadherin EGF LAG seven-pass G-type receptor 3;Cadherin family member 11;CDHF11;CELR3_HUMAN;CELSR3;EGF-like protein 1;EGFL1;Epidermal growth factor-like protein 1;Flamingo;Flamingo homolog 1;FMI1;HFMI1;MEGF2;Multiple EGF-like domains protein 2;Multiple epidermal growth factor-like domains protein 2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：Drosophila Flamingo is a seven pass transmembrane cadherin that is necessary for dendritic patterning ａnd axon guidance. Flamingo mammalian homo-logs play similar roles in neuronal development, during which they play an important role in cell-cell signaling. Cadherin EGF LAG seven pass G-type receptors （CELSRs） are multi-pass membrane proteins that belong to the G protein-coupled receptor family of proteins. Silencing CELSR2 gene ex-pression results in signficant simplification of dendritic arbors of cortical pyramidal neurons ａnd Purkinje neurons, which may be due to branch retraction. In mouse, CELSR1, CELSR2 ａnd CELSR3 are expressed in the nervous system at early developmental stages, ａnd show expression patterns in the developing CNS. CELSR2 is distributed at intercellular boundaries in the whisker ａnd on processes of neuronal cells such as hippocampal pyramidal cells, Purkinje cells ａnd olfactory neurons.Function : Receptor that may have an important role in cell/cell signaling during nervous system formation.Subcellular Location : Cell membrane.Similarity : Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.Contains 9 cadherin domains.Contains 8 EGF-like domains.Contains 1 GPS domain.Contains 1 laminin EGF-like domain.Contains 2 laminin G-like domains."
