产品展示
CD66a/CEACAM1癌胚抗原相关细胞粘附分子1抗体
点击次数:303发布时间:2012/12/3 21:36:07
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-4896R
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详细内容
货号:BY-4896R
英文名称:Anti-CD66a/CEACAM1
中文名称:癌胚抗原相关细胞粘附分子1抗体
其他名称:carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1 precursor; Antigen CD66; BGP; BGP 1; BGP I; BGP1;BGPI; Biliary glycoprotein 1; Biliary glycoprotein adhesion molecule; Biliary glycoprotein; Carcinoembryonic antigen related cell adhesion molecule 1; CD66 antigen; CD66a antigen; CEACAM 1; bb-1; C-CAM; Cc1; Cea-1; Cea-7; Cea1; Cea7; Hv-2; Hv2; mCEA1; Mhv-1; MHVR; MHVR1; mmCGM1; mmCGM1a; mmCGM2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 57kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:This gene encodes a member of the carcinoembryonic antigen(CEA) gene family, which belongs to the immobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bunoglile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq].Subcellular Location : Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Cell membrane; Single-pass type I membrane protein. Isoform 6: Cell membrane; Single-pass type I membrane protein. Isoform 7: Cell membrane; Single-pass type I membrane protein. Isoform 8: Cell membrane; Single-pass type I membrane protein. Note=Localizes to sites of cell-cell contact.Similarity : Belongs to the immunoglobulin superfamily. CEA family.