产品展示
CDNF/ARMETL1脑多巴胺神经营养因子抗体
点击次数：247发布时间：2012/12/3 21:36:25
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-11499R
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详细内容
货号：BY-11499R
英文名称：Anti-CDNF/ARMETL1
中文名称：脑多巴胺神经营养因子抗体
其他名称：Arginine rich mutated in early stage tumors like 1;ARMET L1;ARMET like protein 1;ARMET-like protein 1;ARMETL 1;Cdnf;CDNF_HUMAN;Cerebral dopamine neurotrophic factor;Conserved dopamine neurotrophic factor.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：CDNF is an ARMET family member that is known to be a trophic factor for dopamine neurons. CDNF has been shown to prevent the 6-hydroxydopamine （6-OHDA）-induced degeneration of dopaminergic neurons. CDNF application will restore the dopaminergic function that is reduced by lesions formed from administering 6-OHDA. CDNF further prevents the degeneration of dopaminergic neurons in substantia nigra. CDNF is expressed at high levels in the heart, skeletal muscle, testis ａnd brain. In brain, CDNF has selective expression with the highest being detected in the Purkinje cells of the cerebellum ａnd in regions of the brain stem, including the locus coeruleus.Function : Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine （6-OHDA）-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function ａnd prevents the degeneration of dopaminergic neurons in substantia nigra.Subcellular Location : Secreted.Tissue Specificity : Widely expressed in neuronal ａnd non-neuronal tissues. In the brain, highest levels in the optic nerve ａnd corpus callosum.Similarity : Belongs to the ARMET family."
