本公司经销CYP2C9，细胞色素P450 2C9抗体，克隆类型为polyclonal，宿主来源是Rabbit，CYP2C9细胞色素P450 2C9抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-2887R
英文名称：Anti-CYP2C9
中文名称：细胞色素P450 2C9抗体
其他名称：Cytochrome P450 2C9; The Cytochrome P450 （P450） superfamily of enzymes is one of three enzyme CPC9; CYP2C; CYP2C10; CYP2C9; Cytochrome p4502C9; P450 MP; P450 PB 1; P450 PB1; P450IIC9; P450MP; S mephenytoin 4 hydroxylase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 54kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo
产品介绍：CYP2C9 localizes to the endoplasmic reticulum ａnd its expression is induced by rifampin. In liver microsomes, this enzyme oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, ａnd xenobiotics. CYP2C9 is known to contribute to the wide pharmacokinetics variability of the metabolism of drugs ａnd is involved in the metabolism of drugs such as ibuprufen, S-warfarin, diclofenac, phenytoin, tolbutamide ａnd losartan.The Cytochrome P450 （P450） superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid （AA） to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate （NADPH） ａnd P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid （EETs） ａnd omega-hydroxylases are those P450s which produce 19- ａnd 20-hydroxyeicosatetraenoic acids （19- ａnd 20-HETE）. As well as fatty acid metabolism, P450s also metabolize many drugs ａnd toxins. Cytochrome P450 3A4 is abundantly expressed in liver ａnd small intestine ａnd is inducible by barbiturates, glucocorticoids ａnd rifampicin. Subcellular Location : Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.Similarity : Belongs to the cytochrome P450 family.产品图片Antigen: bs-2887P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bs-0295G-HRP） at 1: 5000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm.