产品展示
CYP2D6细胞色素P450 2D6抗体
点击次数：266发布时间：2012/12/3 21:51:04
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-2991R
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详细内容
货号：BY-2991R
英文名称：Anti-CYP2D6
中文名称：细胞色素P450 2D6抗体
其他名称：Cytochrome P450 2D6; CPD6; CYP2D; CYP2D6; CYP2DL1; CYPIID6; Cytochrome P450 family 2 subfamily D polypeptide 6; Debrisoquine 4 hydroxylase; EC 1.14.14.1; Flavoprotein linked monooxygenase; MGC120389; MGC120390; Microsomal monooxygenase; P450 DB1; P450C2D; P450DB1; Xenobiotic monooxygenase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 55kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, shp, cat, cow, Rb, hrs, pig
产品介绍：commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine ａnd propafe, both anti-arrythmic drugs; ａnd amitryptiline, an anti-depressant. The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme＇s substrates.Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" （LKM 1）. Subcellular Location : Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.Similarity : Belongs to the cytochrome P450 family.产品图片Antigen: bs-2991P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bs-0295G-HRP） at 1: 5000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm.
