产品展示
CTGFL结缔组织生长因子样蛋白抗体
点击次数：237发布时间：2012/12/3 22:00:10
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-5100R
优质供应
详细内容
货号：BY-5100R
英文名称：Anti-CTGFL
中文名称：结缔组织生长因子样蛋白抗体
其他名称：CCN family member 5; CCN5; Connective tissue growth factor like protein; Connective tissue growth factor related protein 58; Connective tissue growth factor-like protein; Connective tissue growth factor-related protein 58; CT58; CTGF L; CTGFL; CTGF-L; WISP 2; WISP-2; Wisp2; WISP2_HUMAN; WNT1 inducible signaling pathway protein 2; WNT1-inducible-signaling pathway protein 2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 27kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：WISP2 a member of the WNT1 inducible signaling pathway （WISP） protein subfamily, which belongs to the connective tissue growth factor （CTGF） family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain ａnd C-terminal cystine knot-like （CT） domain. WISP2 lacks the CT domain which is implicated in dimerization ａnd heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, ａnd may play an important role in modulating bone turnover.
