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C19orf4619号染色体开放阅读框46抗体
点击次数：302发布时间：2012/12/3 22:02:41
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9682R
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详细内容
货号：BY-9682R
英文名称：Anti-C19orf46
中文名称：19号染色体开放阅读框46抗体
其他名称：Nesprin-4;Nesprin4;Nesprin 4;Chromosome 19 open reading frame 46;FLJ36445;Hypothetical protein LOC163183.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 43kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, cow
产品介绍：C19orf46 is a 404 amino acid single-pass type IV membrane protein that belongs to the nesprin family. C19orf46 partcipates in the establishment of secretory epithelial morphology by inducing kinesin-dependent apical migration of the centrosome ａnd Golgi apparatus as well as basal localization of the nucleus. C19orf46 interacts with UKHC ａnd KCL1, ａnd exists as two alternatively spliced isoforms. C19orf46 contains a KASH domain, which consists of a transmembrane motif, mediates nuclear enevelop targeting ａnd binds to the SUN domain of SUN1 ａnd SUN2. C19orf46 is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases ａnd makes up over 2% of human genomic DNA.Subcellular Location : Nucleus membrane; Single-pass type IV membrane protein
