产品展示
CRCT1富含半胱氨酸C端蛋白1抗体
点击次数：347发布时间：2012/12/3 22:05:16
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9956R
优质供应
详细内容
货号：BY-9956R
英文名称：Anti-CRCT1
中文名称：富含半胱氨酸C端蛋白1抗体
其他名称：C1orf42;CRCT1;CRCT 1;CRCT-1;CRCT1_HUMAN;Cysteine rich C terminal 1;Cysteine-rich C-terminal protein 1;NICE 1;NICE1;NICE-1;Protein NICE-1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 10kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：Chromosome 1 is the largest human chromosome spanning about 260 million base pairs ａnd making up 8% of the human genome. There are about 3,000 genes on chromosome 1, ａnd considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus ａnd cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear ａnd is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 ａnd is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease ａnd Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene ａnd is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head ａnd neck cancer, malignant melanoma ａnd multiple myeloma.
