产品展示
CREG2E1A激活基因刺激蛋白2抗体
点击次数：278发布时间：2012/12/3 22:05:35
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9957R
优质供应
详细内容
货号：BY-9957R
英文名称：Anti-CREG2
中文名称：E1A激活基因刺激蛋白2抗体
其他名称：CREG 2;CREG-2;Cellular repressor of E1A stimulated genes 2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 32kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：The adenovirus E1A protein both activates ａnd represses gene expression to promote cellular proliferation ａnd inhibit differentiation. CREG （cellular repressor of E1A-stimulated genes） is a cellular protein that antagonizes transcriptional activation ａnd cellular transformation by E1A. CREG was initially isolated in a yeast two-hybrid screen due to its interaction with the TATA-binding protein, TBP. A member of the CREG family, CREG2 （cellular repressor of E1A-stimulated genes 2） is a novel protein that shares 35% homology with CREG ａnd is expressed at highest levels in brain. CREG2 is a secreted protein containing 290 amino acids whose N-terminus is thought to function as a signal sequence. The gene encoding CREG2 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes ａnd makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia ａnd Alstr鰉 syndrome.Tissue Specificity : Secreted.
