产品展示
CARM1蛋白精氨酸N甲基4抗体
点击次数：205发布时间：2012/12/3 22:08:22
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-4098R
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详细内容
货号：BY-4098R
英文名称：Anti-CARM1
中文名称：蛋白精氨酸N甲基4抗体
其他名称：CARM1_HUMAN; Coactivator associated arginine methyltransferase 1; Coactivator-associated arginine methyltransferase 1; Histone arginine methyltransferase CARM 1; Histone arginine methyltransferase CARM1; Histone-arginine methyltransferase CARM1; PRMT 4; Protein arginine methyltransferase; Protein arginine N methyltransferase 4; Protein arginine N-methyltransferase 4.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 50-63kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, pig, dog
产品介绍：Methylates （mono- ａnd asymmetric dimethylation） the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, ａnd mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 ａnd p160 families, methylates histone H3 at ＇Arg-17＇ ａnd activates transcription via chromatin remodeling. During nuclear hormone receptor activation ａnd TCF7L2/TCF4 activation, acts synergically with EP300/P300 ａnd either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 ａnd NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C.
