产品展示
Phospho-CDK9 (Thr29)磷酸化周期素依赖性激酶9抗体
点击次数：244发布时间：2012/12/3 22:12:20
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-5249R
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详细内容
货号：BY-5249R
英文名称：Anti-Phospho-CDK9 （Thr29）
中文名称：磷酸化周期素依赖性激酶9抗体
其他名称：CCN T1; CCNT; CCNT 1; CCNT1; CDK9 associated C type protein; Cyc T1; Cyclin C related protein;cyclin T; cyclin T1; Cyclin T1b; Cyclin-T; cyclin-T1; ; CYCT 1; cycT1; HIVE1; Human immunodeficiency virus 1 expression; Human immunodeficiency virus type 1 （HIV 1） expression （elevated） 1; pTEFb subunit; Subunit of positive elongation transcription factor b.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 85kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression ａnd degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, ａnd was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin ａnd the elongation factor can interact with, ａnd act as a cofactor of human immunodeficiency virus type 1 （HIV-1） Tat protein, ａnd was shown to be both necessary ａnd sufficient for full activation of viral transcription. This cyclin ａnd its kinase partner were also found to be involved in the phosphorylation ａnd regulation of the carboxy-terminal domain （CTD） of the largest RNA polymerase II subunit.Cdk9-周期素依赖激酶9（Cyclin Dependent Kinase 9），同样是参与细胞周期的调控，在细胞分化、有丝分裂中起重要作用。
