产品展示
CKMT/Creatine kinase MT酸性型线粒体肌酸激酶抗体
点击次数:410发布时间:2012/12/3 22:15:07
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-6522R
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货号:BY-6522R
英文名称:Anti-CKMT/Creatine kinase MT
中文名称:酸性型线粒体肌酸激酶抗体
其他名称:Acidic type mitochondrial creatine kinase; CKMT; CKMT1; CKMT1A; CKMT1B; Creatine kinase mitochondrial 1 ubiquitous; Creatine kinase ubiquitous mitochondrial; Mia CK; Ubiquitous mitochondrial creatine kinase; UMTCK.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 47kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:Creatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.