产品展示
C11orf5711号染色体开放阅读框57抗体
点击次数：272发布时间：2012/12/3 22:18:16
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9939R
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详细内容
货号：BY-9939R
英文名称：Anti-C11orf57
中文名称：11号染色体开放阅读框57抗体
其他名称：chromosome 11 open reading frame 57;CK057_HUMAN;FLJ10726;hypothetical protein LOC55216;Uncharacterized protein C11orf57.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 25kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：C11orf57, also known as FLJ10726, is a 292 amino acid protein that exists as three alternatively spliced isoforms ａnd is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs ａnd 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA ａnd is considered a gene ａnd disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest ａnd apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia ａnd β thalassemia are caused by HBB gene mutations. Wilms＇ tumors, WAGR syndrome ａnd Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell ａnd Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema ａnd Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
