产品展示
CLECSF9/CLEC 4EC型凝集素4家族E抗体
点击次数:403发布时间:2012/12/3 22:21:47
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-8541R
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货号:BY-8541R
英文名称:Anti-CLECSF9/CLEC 4E
中文名称:C型凝集素4家族E抗体
其他名称:C type lectin domain family 4 member E; C type lectin superfamily member 9; C-type (calcium dependent carbohydrate recognition domain) lectin superfamily member 9; C-type lectin domain family 4 member E; C-type lectin superfamily member 9; CLC4E_HUMAN; CLEC 4E; CLEC4E Clec4e; CLECSF9; Macrophage inducible C type lectin; Macrophage-inducible C-type lectin; MINCLE.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 25kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, cow
产品介绍:C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.Function : C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.Subunit : Monomer. Homodimer.Subcellular Location : Membrane.Similarity : Contains 1 C-type lectin domain.