产品展示
CD158eNK细胞抑制性受体3DL1抗体
点击次数：247发布时间：2012/12/5 10:35:10
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-2421R
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详细内容
货号：BY-2421R
英文名称：Anti-CD158e
中文名称：NK细胞抑制性受体3DL1抗体
其他名称：KIR3DL1; Killer cell immunoglobulin-like receptor 3DL1; AMB11; CD158 antigen-like family member E; CD158E; CD158e antigen; CD158E1; CD158E1/2; CD158E2; CL11; CL2; HLA-BW4-specific inhibitory NK cell receptor; killer cell immunoglobulin like receptor; Killer cell immunoglobulin like receptor three domains , short cytoplasmic tail, 1; Killer cell immunoglobulin like receptor three domains long cytoplasmic tail 1; KIR; KIR antigen 3DL1; KIR G1; KIR3DS1; Kirl1; Kirl2; Krl1; MGC119726; MGC119728; MGC126589; MGC126591; MHC class I NK cell receptor; Natural killer associated transcript 3; Natural killer cell inhibitory receptor; NK receptor; NK-associated transcript 10; NK-associated transcript 3; NK-associated transcript 3delIg1; NKAT10; NKAT3; NKB1; NKB1B; p70 killer cell inhibitory receptor; p70 natural killer cell receptor clones CL 2/CL 11
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 49kDa
纯化方法：affinity purified by Protein A
交叉反应：rat, mo
产品介绍：KIR3DL1 （NKB1, CD158e1） is expressed on a subset of natural killer cells ａnd T cells. NKB1 is a 70 kD member of the immunoglobulin superfamily that is expressed at varying levels among individuals. NKB1 is a type I membrane protein containing two immunoglobulin C2 type domains. The interaction of NKB1 with specific HLA B antigens on a target cell （the HLA Bw4 allele, for example） inhibits cytotoxicity ａnd prevents target cell lysis ａnd death. The interactions between KIR ａnd MHC class I are thought to be important in NK ａnd T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors ａnd increase inflammation ａnd susceptibility to autoimmune disease.
