产品展示
CD1a/Cortical thymocyte antigen CD1AT淋巴细胞CD1抗体
点击次数：229发布时间：2012/12/5 10:50:54
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-3786R
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详细内容
货号：BY-3786R
英文名称：Anti-CD1a/Cortical thymocyte antigen CD1A
中文名称：T淋巴细胞CD1抗体
其他名称： CD1D; A1 domain; CD1A; CD1A antigen; CD1B; CD1b antigen; CD1b molecule; CD1C; CD1C antigen; CD1c molecule; CD1d molecule; Cd1d1; Cortical thymocyte antigen CD1A; Cortical thymocyte antigen CD1B; Cortical thymocyte antigen CD1C; Cortical thymocyte antigen CD1D; hTa1 thymocyte antigenLy38; Ly38; T cell surface glycoprotein CD1a; T cell surface glycoprotein CD1b; T cell surface glycoprotein CD1c; T cell surface glycoprotein CD1d; T6/Leu6.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 34kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex （MHC） proteins ａnd form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid ａnd glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization ａnd specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq].Subcellular Location : Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane ａnd endosomes. Localizes to cell surface lipid rafts.Tissue Specificity : Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, ａnd in various other tissues.Similarity : Contains 1 Ig-like （immunoglobulin-like） domain.
