产品展示
CYP3A1细胞色素P450 3A1抗体
点击次数：312发布时间：2012/12/5 10:51:35
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-2375R
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详细内容
货号：BY-2375R
英文名称：Anti-CYP3A1
中文名称：细胞色素P450 3A1抗体
其他名称：CP33; CP34; CYP3A; CYP3A1; CYP3A3; CYP3A4; CYPIIIA4; Cytochrome P450 3A4; Cytochrome P450 family 3 subfamily A polypeptide 4; Cytochrome P450 subfamily IIIA polypeptide 3; Cytochrome P450 subfamily IIIA polypeptide 4; cytochrome P450, family 3, subfamily a, polypeptide 1; glucocorticoid inducible P450; HLP antibody MGC126680; NF 25; NF25; Nifedipine oxidase; Niphedipine oxidase; P450 III steroid inducible; P450 PCN（PCNC inducible）; P450 PCN1; P450C3; P450PCN1; Quinine 3 monooxygenase; Taurochenodeoxycholate 6 alpha hydroxylase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 56kDa
纯化方法：affinity purified by Protein A
交叉反应：rat, mo, hrs, cow, dog, shp, chk
产品介绍：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism ａnd synthesis of cholesterol, steroids ａnd other lipids. This protein localizes to the endoplasmic reticulum ａnd its expression is induced by glucocorticoids ａnd some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam ａnd erythromycin. The enzyme also metabolizes some steroids ａnd carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].Subcellular Location : Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.Similarity : Belongs to the cytochrome P450 family.
