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Cytochrome P450 2D1细胞色素CYP2D1抗体
点击次数:250发布时间:2012/12/5 10:51:55
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-4108R
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货号:BY-4108R
英文名称:Anti-Cytochrome P450 2D1
中文名称:细胞色素CYP2D1抗体
其他名称:CPD6; CYP2D; Cyp2d1; Cyp2d9; CYPIID6; Cytochrome P450 2D1; Cytochrome P450 2D6; Debrisoquine 4 hydroxylase; P450 DB1; xenobiotic monooxygenase.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 55kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, Rb
产品介绍:The cytochrome P450 superfamily of heme thiolate mono oxygenases play a key role in the oxidative metabolism of many endogenous and exogenous molecules, and are classified by their primary structure into four main groups. It is an ancient superfamily, which has been identified in prokaryotes and in many types of eukaryotic cells.The CYP2A sub family is found in the liver, and recently in the nasal mucosa where they are involved in the metabolism of inhaled xenobiotics and nicotine. CYP2B proteins are found in the liver, where they are involved in the metabolism of hepatic drugs, and in the lung and brain, whereas the CYP2C proteins are involved in the metabolism of anti depressants. CYP2E1 is alcohol inducible, and found principally in the liver.Subcellular Location : Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.Similarity : Belongs to the cytochrome P450 family.