产品展示
CDC34B/UBC3B泛素载体蛋白R2抗体
点击次数:244发布时间:2012/12/5 10:52:27
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-3813R
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详细内容
货号:BY-3813R
英文名称:Anti-CDC34B/UBC3B
中文名称:泛素载体蛋白R2抗体
其他名称:CDC34B; E2 CDC34B; UBE2R2; Ubiquitin carrier protein R2; Ubiquitin conjugating enzyme E2 CDC34B; Ubiquitin conjugating enzyme E2 R2; Ubiquitin conjugating enzyme E2R 2; Ubiquitin conjugating enzyme UBC3B; Ubiquitin protein ligase R2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 26kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, chk, Rb
产品介绍:UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.Function : Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin.Subunit : When phosphorylated, interacts with beta-TrCP (BTRC).Similarity : Belongs to the ubiquitin-conjugating enzyme family.