产品展示
CNOT4细胞表面趋化因子受体4相关蛋白4抗体
点击次数：249发布时间：2012/12/5 10:55:31
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9285R
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详细内容
货号：BY-9285R
英文名称：Anti-CNOT4
中文名称：细胞表面趋化因子受体4相关蛋白4抗体
其他名称：CCR4 NOT transcription complex subunit 4;CCR4-associated factor 4;CCR4-NOT transcription complex subunit 4;CLONE243;CNOT 4;Cnot4;CNOT4_HUMAN;E3 ubiquitin-protein ligase CNOT4;NOT 4;NOT4 （negative regulator of transcription 4 yeast） homolog;NOT4;NOT4H;Potential transcriptional repressor NOT4Hp.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 63kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription as well as mRNA degradation. Various subunits within the complex are involved in influencing nuclear hormone receptor activities. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome. CNOT4 （CCR4-NOT transcription complex subunit 4）, also known as CCR4-associated factor 4 ａnd E3 ubiquitin-protein ligase CNOT4, is a 575 amino acid protein that is a subunit of the CCR4-NOT complex. CNOT4 contains one C3H1-type zinc finger, one RING-type zinc finger ａnd one RRM （RNA recognition motif） domain. Via its RING domain, CNOT4 binds E2 ubiquitin ligases. CNOT4 functions as a UbcH5B-dependent ubiquitin-protein ligase （E3 ligase）. There are eight isoforms of CNOT4 that are expressed as a result of alternative splicing events.Subcellular Location : Cytoplasm. Nucleus.
