本公司经销Calpain 2，钙激活的中性蛋白酶2抗体，克隆类型为polyclonal，宿主来源是Rabbit，Calpain 2钙激活的中性蛋白酶2抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-1599R
英文名称：Anti-Calpain 2
中文名称：钙激活的中性蛋白酶2抗体
其他名称：Calcium activated neutral proteinase 2; Calcium activated neutral proteinase; CALP80; Calpain 2 （m/II） large subunit; Calpain 2 catalytic subunit; Calpain 2 large catalytic subunit; Calpain 2 large subunit; Calpain large polypeptide L2; Calpain M type; Calpain2; CANP 2; CANP L2; CANP2; CANPL 2; CANPL2; CANPml; Capa2; CAPN 2; CAPN2; FLJ39928; M calpain; M calpin; M type; mCANP; Millimolar calpain
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 77kDa
纯化方法：affinity purified by Protein A
交叉反应：mo, rat, hu, cow, shp, dog
产品介绍：Calpain, ａnd m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity （thus the mu） as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 ａnd 2 are composed of an 80 kD subunit ａnd a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different ａnd exhibit the distinct Ca++ requirements that are suggested by their names. The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 ａnd Calpain 2 are ubiquitously expressed, ａnd are countered by the endogenous calpain inhibitor, calpastatin. Other calpain family members （calpain 94, ncl2, ncl3, etc） have more limited tissue distribution, ａnd perhaps different functions. The calpain family members consist of a common small subunit （Calpain 4）, ａnd a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, ａnd the EF hand domain IV. The calpains appear to serve multiple physiological roles, ａnd ideas concerning the functions of these enzymes are in a state of rapid flux.钙蛋白酶2（calpain2）也是一族钙离子依赖性的、水解半胱氨酸的蛋白酶,广泛存在于全身各脏器组织中。钙蛋白酶参与不同细胞过程,包括细胞骨架和细胞膜附着的构型重建、不同的信号转导途径和细胞凋亡等.