产品展示
C1orf2/COTE11号染色体开放阅读框2抗体
点击次数：195发布时间：2012/12/5 11:04:47
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9782R
优质供应
详细内容
货号：BY-9782R
英文名称：Anti-C1orf2/COTE1
中文名称：1号染色体开放阅读框2抗体
其他名称：Chromosome 1 open reading frame 2; COTE1; F189B_HUMAN; FAM189B; Family with sequence similarity 189 member B; Hypothetical protein LOC10712; Protein COTE1; Protein FAM189B.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 71kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, cow, hrs, Rb, Gpig, pig
产品介绍：COTE1, also known as FAM189B （family with sequence similarity 189, member B）, is a 668 amino acid multi-pass membrane protein that is widely expressed ａnd belongs to the FAM189 family. Existing as two alternatively spliced isoforms, COTE1 is encoded by a gene that maps to human chromosome 1q22. As the largest human chromosome, chromosome 1 spans about 260 million base pairs ａnd makes up approximately 8% of the human genome. Hutchinson-Gilford progeria, a rare aging disorder, is associated with the LMNA gene which is located on chromosome 1. Familial adenomatous polyposis, Stickler syndrome, Parkinsons, Gaucher disease ａnd Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head ａnd neck cancer, malignant melanoma ａnd multiple myeloma.Subcellular Location : Membrane.Tissue Specificity : Widely expressed.
