产品展示
C1orf19/SEN151号染色体开放阅读框19抗体
点击次数：172发布时间：2012/12/5 11:05:04
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9783R
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详细内容
货号：BY-9783R
英文名称：Anti-C1orf19/SEN15
中文名称：1号染色体开放阅读框19抗体
其他名称：Chromosome 1 open reading frame 19;Chromosome 1 open reading frame 19, isoform CRA_c;HsSen15;sen15;SEN15 homolog;SEN15_HUMAN;tRNA intron endonuclease Sen15;tRNA splicing endonuclease 15 homolog （S. cerevisiae）;tRNA splicing endonuclease subunit Sen15;tRNA-intron endonuclease SEN15;tRNA-splicing endonuclease subunit SEN15;Tsen15.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 19kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：SEN15, also known as TSEN15 （tRNA-splicing endonuclease subunit Sen15） or C1orf19, is a nuclear protein that plays a role in tRNA splicing. Widely expressed with highest expression in testis ａnd uterus, SEN15 is a non-catalytic subunit of the multi-protein tRNA-splicing endonuclease complex. The endonuclease complex is responsible for identifying ａnd cleaving pre-tRNA at both 5’ ａnd 3’ splice sites, thereby releasing introns ａnd free tRNA molecules with 2＇,3＇ cyclic phosphates ａnd 5＇-OH termini. In addition to its role in pre-tRNA splicing, the endonuclease complex participates in mRNA processing and, via its association with pre-mRNA processing factors, is thought to link pre-tRNA ａnd pre-mRNA splicing events. As a subunit of the complex, SEN15 participates in protein expression and, ultimately, cell growth ａnd division.Subcellular Location : Nucleus.Tissue Specificity : Widely expressed. Highly expressed in testis ａnd uterus.
