产品展示
C1orf521号染色体开放阅读框52抗体
点击次数：147发布时间：2012/12/5 11:06:13
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9787R
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详细内容
货号：BY-9787R
英文名称：Anti-C1orf52
中文名称：1号染色体开放阅读框52抗体
其他名称：FLJ44982; RP11-234D19.1;BAG;BCL10 associated gene protein;C1orf52;Chromosome 1 open reading frame 52;gm117;Hypothetical protein LOC148423;UPF0690 protein C1orf52.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 21kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：Belonging to the UPF0690 family, C1orf52 is a 182 amino acid protein that is expressed in liver, heart, skeletal muscle, pancreas ａnd kidney. There are three isoforms of C1orf52 that are produced as a result of alternative splicing events. The gene encoding C1orf52 maps to chromosome 1, the largest human chromosome spanning about 260 million base pairs ａnd making up 8% of the human genome. There are about 3,000 genes on chromosome 1, ａnd considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus ａnd cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear ａnd is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 ａnd is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease ａnd Usher syndrome are also associated with chromosome 1.
