产品展示
CD33/Siglec-3CD33抗体
点击次数：638发布时间：2012/12/5 11:07:26
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-4884R
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详细内容
货号：BY-4884R
英文名称：Anti-CD33/Siglec-3
中文名称：CD33抗体
其他名称：CD 33;CD33;CD33 antigen （gp67）;CD33 antigen;CD33 molecule;CD33_HUMAN;FLJ00391;gp67;My9;Myeloid cell surface antigen CD33;Myeloid cell surface antigen CD33 precursor;Sialic acid binding Ig like lectin 3;Sialic acid binding immunoglobulin like lectin 3;Sialic acid-binding Ig-like lectin 3;SIGLEC 3;Siglec-3;SIGLEC3.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 40kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase（s） via their SH2 domain（s） that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia.Subcellular Location : Cell membrane.Tissue Specificity : Monocytic/myeloid lineage cells.
