产品展示
CANX/Calnexin钙连蛋白抗体
点击次数：441发布时间：2012/12/5 11:20:07
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-1693R
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货号：BY-1693R
英文名称：Anti-CANX/Calnexin
中文名称：钙连蛋白抗体
其他名称：Calnexin - ER membrane marker; CALNEXIN; CANX; Cell adhesion molecule with homology to l1cam precursor; CNX; D11Ertd153e; 1110069N15Rik; AI988026; FLJ26570; IP90; P90; Similar to calnexin.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 63kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：ER membrane marker This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum （ER）-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding ａnd assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]Function : Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.Subcellular Location : Endoplasmic reticulum membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.内质网膜蛋白标志物（ER membrane marker） 钙连蛋白 calnexin 存在于内质网中，是内质网膜标志物，属于Ca2+的凝集素样分子伴侣蛋白，可结合蛋白质的寡糖链 ，防止蛋白质彼此聚集和泛素化，避免折叠不完全的蛋白质离开内质网。
