本公司经销Collagen IV/Arresten，抗IV型胶原抗体，克隆类型为polyclonal，宿主来源是Rabbit，Collagen IV/Arresten抗IV型胶原抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0806R
英文名称：Anti-Collagen IV/Arresten
中文名称：抗IV型胶原抗体
其他名称：Arresten; Canstatin; COL4A1; COL4A2; COL4A3; COL4A4; COL4A5; Collagen Alpha 1（IV） Chain; Collagen Alpha 2（IV） Chain; Collagen IV Alpha 1 Polypeptide; Collagen IV Alpha 2 Polypeptide; Collagen Of Basement Membrane Alpha 1 Chain; Collagen Of Basement Membrane Alpha 2 Chain; Collagen Type IV Alpha 1; Collagen Type IV Alpha 2; Collagen Type IV Alpha 3; Collagen Type IV Alpha 4; Collagen Type IV Alpha 5; DKFZp686I14213; FLJ22259.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 184kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, pig, dog, hrs
产品介绍：Collagen IV is a major constituent of the basement membranes along withlaminins, proteoglycans ａnd enactins. It is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. It can form insoluble fibers with high tensile strength. Collagen IV is useful in detecting the loss of parts of basement membranes in carcinomas.Subunit : There are six type IV collagen isoforms, alpha 1（IV）-alpha 6（IV）, each of which can form a triple helix structure with 2 other chains to generate type IV collagen network.Subcellular Location : Secreted, extracellular space, extracellular matrix, basement membrane.Similarity : Contains 1 FAD-binding FR-type domain.Contains 1 ferric oxidoreductase domain.IV型胶原为基底膜的主要成分，主要用于各种良恶性组织（乳腺癌、胃肠道癌等）中基底膜分布情况的研究.IV型胶原是构成基底膜的主要成分。该抗体可特异性识别人的IV型胶原，与人类皮肤、肾、肌肉、脾、淋巴结、胎盘和肺的基底膜呈阳性反应，主要用于各种组织癌症中基底膜情况的研究。产品图片Antigen: bs-0806P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bs-0295G-HRP） at 1: 5000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm. Tissue/cell: rat liver tissue; 4% Paraformaldehyde-fixed ａnd paraffin-embedded; Antigen retrieval: citrate buffer （ 0.01M, pH 6.0 ）, Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer （normal goat serum,C-0005） at 37℃ for 20 min; Incubation: Anti-Collagen IV Polyclonal Antibody, Unconjugated（bs-0806R） 1:200, overnight at 4°C, followed by conjugation to the secondary antibody（SP-0023） ａnd DAB（C-0010） stainingTissue/cell: rabbit cartilage tissue; 4% Paraformaldehyde-fixed ａnd paraffin-embedded; Antigen retrieval: citrate buffer （ 0.01M, pH 6.0 ）, Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer （normal goat serum,C-0005） at 37℃ for 20 min; Incubation: Anti-Collagen IV Polyclonal Antibody, Unconjugated（bs-0806R） 1:200, overnight at 4°C, followed by conjugation to the secondary antibody（SP-0023） ａnd DAB（C-0010） staining