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Calretinin/CA钙结合蛋白抗体
点击次数:247发布时间:2012/12/5 11:34:45
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-0062R
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货号:BY-0062R
英文名称:Anti-Calretinin/CA
中文名称:钙结合蛋白抗体
其他名称:29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; CR.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 29kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, cow, pig, dog, hrs
产品介绍:Calretinin is a calcium-binding protein which is abundant in auditory neurons. It belongs to the calbindin family. Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin1.Function : Calretinin is a calcium-binding protein which is abundant in auditory neurons.Tissue Specificity : Brain.Similarity : Belongs to the calbindin family. Contains 6 EF-hand domains. 钙结合蛋白(Calretinin,CR)主要存在于神经组织中,近10%的腺癌可以表达此蛋白的局部染色阳性,而绝大多数的间皮瘤为阳性表达,因此它是诊断间皮瘤的一个有用的标记物 。 钙结合蛋白是平滑肌和非肌性调控蛋白。它可以与肌动蛋白、肌球蛋白、原肌球蛋白和钙调素相互作用。