产品展示
CRP(C11F2)C-反应蛋白单克隆抗体
点击次数：236发布时间：2012/12/5 11:35:33
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BYm-0391M
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详细内容
货号：BYm-0391M
英文名称：Anti-CRP（C11F2）
中文名称：C-反应蛋白单克隆抗体
其他名称：C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C Reactive Protein.
抗体来源：Mouse
克隆类型：monoclonal克隆号C11F2
蛋白分子量：predicted molecular weight: 25kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin （cyclic pentameric protein） compound of five identical nonglycosylated subunits of 206 amino acids each （m.w. 24 kDa）, that are bound noncovalently to form the physiologic CRP molecule （m.w. 117.5 kDa）. C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade ａnd an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones ａnd snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina ａnd elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein （hsCRP） in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture. C-反应蛋白-CRP（C-reactive protin）是与C性肺炎球菌的多糖起反应的一种蛋白，在某些细菌的感染过程中出现在血浆中。
