产品展示
phospho-Caveolin-2(Tyr19)磷酸化细胞质膜微囊蛋白-2抗体
点击次数:237发布时间:2012/12/5 11:41:52
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-7523R
优质供应
详细内容
货号:BY-7523R
英文名称:Anti-phospho-Caveolin-2(Tyr19)
中文名称:磷酸化细胞质膜微囊蛋白-2抗体
其他名称:Caveolin 2 (phospho Y19); p-Caveolin 2(phospho Y19); CAV; CAV2; CAV2_HUMAN; Caveolae protein 20 kD; Caveolin 2; Caveolin 2 isoform a and b; Caveolin 2 isoform c; Caveolin-2; MGC12294.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 18kDa
纯化方法:affinity purified by Protein A
交叉反应:mo, rat
产品介绍:Cellular localization: Nucleus. Cytoplasm. Golgi apparatus membrane. Cell membrane. Membrane > caveola. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments.Caveolin是细胞生长相关信号途径及肿瘤发生发展过程中重要的抑制因子,Caveolae是细胞膜内的特殊膜结构,参与包括细胞的分子运输、细胞粘附和信号转导在内的多种细胞活动。Caveolin-1是Caveolae中重要的结构蛋白,抑制细胞生长,与多种人类肿瘤发生发展相关的信号分子相互作用。Caveolin在信号转导的整合中起支架蛋白的作用。Caveolin构成了一个蛋白家族,他们是细胞质膜中发夹样结构域的主要结构成分。Caveolin在信号转导的整合中起支架蛋白的作用。至今已经鉴定了3种Caveolin (Caveolin-1、2 和3),它们具有不同的组织分布。