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Cytokeratin 3+12细胞角蛋白3+12抗体
点击次数：301发布时间：2012/12/5 11:50:45
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-2369R
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货号：BY-2369R
英文名称：Anti-Cytokeratin 3+12
中文名称：细胞角蛋白3+12抗体
其他名称：CK 12; CK 3; CK12; CK3; Cytokeratin 12; Cytokeratin 3; K12; K3; keratin 12 （Meesmann corneal dystrophy）; Keratin 12; Keratin 3; Keratin, type I cytoskeletal 12; Keratin, type II cytoskeletal 3; KRT12; KRT3; 65 kDa cytokeratin.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 65 Cytokeratin 3; 54 Cytokeratin 12.kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, pig, cow, Rb, hrs
产品介绍：Cytokeratin 3 is a member of the intermediate filament family of proteins ａnd is a heterotetramer of two type I ａnd two type II keratins. Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12.Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia.Defects in KRT3 ａnd KRT12 are a cause of Meesmann corneal dystrophy （MCD）, an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Symptoms occur in adulthood ａnd include rupture of the corneal microcysts that may lead to photophobia, contact lens intolerance ａnd intermittent diminution of visual acuity. Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann （MCD）
