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CYP24A1细胞色素P450 24A1抗体
点击次数：273发布时间：2012/12/5 11:52:08
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-3899R
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详细内容
货号：BY-3899R
英文名称：Anti-CYP24A1
中文名称：细胞色素P450 24A1抗体
其他名称：24 ohase; CP 24; CP24; CYP 24; CYP24; Cytochrome P450 24A1; Cytochrome P450 24A1 mitochondrial; Cytochrome P450 family 24; Cytochrome P450 family 24 subfamily A polypeptide 1; Cytochrome P450 subfamily XXIV; Cytochrome P450, subfamily XXIV （vitamin D 24-hydroxylase）; EC 1.14.13.n4; Exo mitochondrial protein; MGC126273; MGC126274; P450 CC24; Vitamin D 24 hydroxylase; Vitamin D（3） 24 hydroxylase; 1 25 @dihydroxyvitamin D3 24 hydroxylase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 53/57kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, chk, dog, hrs, pig, Rb, cow
产品介绍：CYP24A1 （cytochrome P450, family 24, subfamily A, polypeptide 1） is a member of the cytochrome P450 superfamily. It is a mitochondrial enzyme responsible for inactivating vitamin D3 metabolites through the C-24 oxidation pathway. In regulating the level of vitamin D3, CYP24A1 plays a role in calcium homeostasis ａnd the vitamin D endocrine system. CYP24A1 also has a role in maintaining calcium homeostasis. It catalyzes the NADPH-dependent 24-hydroxylation of 25-hydroxyvitamin D（3） in the presence of adrenodoxin ａnd NADPH-adrenodoxin reductase.Subcellular Location : Mitochondrion.Similarity : Belongs to the cytochrome P450 family.产品图片Tissue/cell: human cervical carcinoma; 4% Paraformaldehyde-fixed ａnd paraffin-embedded; Antigen retrieval: citrate buffer （ 0.01M, pH 6.0 ）, Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer （normal goat serum,C-0005） at 37℃ for 20 min; Incubation: Anti-CYP24A1 Polyclonal Antibody, Unconjugated（bs-3899R） 1:200, overnight at 4°C, followed by conjugation to the secondary antibody（SP-0023） ａnd DAB（C-0010） staining
