产品展示
Desmoglein 1/DSG1桥粒芯糖蛋白1
点击次数：175发布时间：2012/12/5 13:14:05
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-6725R
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详细内容
货号：BY-6725R
英文名称：Anti-Desmoglein 1/DSG1
中文名称：桥粒芯糖蛋白1
其他名称：Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal Glycoprotein 1; DG1; DGI; DSG; DSG1; DSG1_HUMAN; Pemphigus Foliaceus Antigen; PPKS1; SPPK1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 110kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins ａnd intermediate filaments mediating cell-cell adhesion.Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 （SPPK1） [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms ａnd soles, ａnd longitudinal hyperkeratotic lesions on the palms, running the length of each finger.Subcellular Location : Cell membrane; Single-pass type I membrane protein （By similarity）. Cell junction, desmosome.Tissue Specificity : Epidermis, tongue, tonsil ａnd esophagus.Similarity : Contains 4 cadherin domains.
