产品展示
DAT1/LIM domain only 3神经细胞特异性转录因子DAT1抗体
点击次数:247发布时间:2012/12/5 13:16:53
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-5938R
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货号:BY-5938R
英文名称:Anti-DAT1/LIM domain only 3
中文名称:神经细胞特异性转录因子DAT1抗体
其他名称:DAT 1; DAT1; LIM domain only 3 (rhombotin like 2); LIM domain only protein 3; LMO 3; LMO3; Neuronal specific transcription factor DAT1; RBTN 3; RBTN3; RBTNL 2; RBTNL2; RHOM 3; RHOM3; Rhombotin 3; Rhombotin like 2; Rhombotin3; LMO3_HUMAN.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 16kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, chk, pig, dog, hrs, cow
产品介绍:LIM domain only 3 (LMO3) belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. It is transcribed mainly in the brain. It interacts with the neuronal transcription factor, HEN2, and acts as an oncogene in neuroblastoma.Function : Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.Subcellular Location : Membrane.DISEASE : Defects in SLC6A3 are the cause of dystonia-parkinsonism infantile (DYTPRI) [MIM:613135]. It is a neurodegenerative disorder characterized by infantile onset of parkinsonism and dystonia. Other neurologic features include global developmental delay, bradikinesia and pyramidal tract signs.Similarity : Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.