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Dio3甲状腺素5´脱碘酶3抗体
点击次数：214发布时间：2012/12/5 13:19:19
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-3902R
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货号：BY-3902R
英文名称：Anti-Dio3
中文名称：甲状腺素5＇脱碘酶3抗体
其他名称：名Type 3 DI; D3; 5DIII; Deiodinase iodothyronine type 3; Deiodinase iodothyronine type III; Dio 3; DIOIII; MGC124117; MGC124118; TXDI3; Type III 5＇ deiodinase; Type III iodothyronine deiodinase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 31kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, shp, cow, pig
产品介绍：Dio3 belongs to the iodothyronine deiodinase family. It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine （T4） ａnd the bioactive hormone 3,3＇,5-triiodothyronine （T3） to inactive metabolites, 3,3＇,5＇-triiodothyronine （RT3） ａnd 3,3＇-diiodothyronine （T2）, respectively. Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones ａnd has been linked to the development of consumptive hypothyroidism in both infants ａnd adults.Subunit : Homodimer. May undergo minor heretodimerization with DIO1 ａnd DIO2.Subcellular Location : Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.Tissue Specificity : Expressed in placenta ａnd several fetal tissues.Similarity : Belongs to the iodothyronine deiodinase family.
